If you need to prototype an audio interaction in Axure RP, it’s totally doable! Imagine this as having a click sound for your button or playing a music or a song during the whole user experience with your prototype.
Though it’s not possible to create a voice-enabled interaction or multimodal prototype (you can do this for example in Adobe XD), there’s a few options for how you can work with an audio in Axure RP.
Just recently I stumbled into this video by VAExperience on Youtube where you can see how to create a prototype with audio clips.
Go and check this great tutorial out!